What is Mesoneedling?
Mesoneedling is an advanced technique that combines microneedling and mesotherapy to help rejuvenate the skin and reduce wrinkles. The term consists of two parts: “meso” and “needling,” meaning the use of needles. In this method, very fine needles scratch the surface of the skin and create small wounds, after which nourishing cocktails are applied to the skin. This process stimulates collagen production in the skin. In fact, these needles, by creating microscopic channels in the deeper layers of the skin, greatly enhance the absorption of nutrients. Over time, the result of this treatment is improved radiance, beauty, and youthfulness of the skin.
How Mesoneedling Works
Mesoneedling is a modern and effective method in the field of beauty and skin treatment, used for rejuvenation and improving skin condition. The way mesoneedling works is that, first, very fine and small needles penetrate the skin using a special device and create microscopic wounds. These superficial wounds activate the skin’s natural healing process and increase the production of collagen and elastin. In the next step, nourishing cocktails containing nutrients, vitamins, and other beneficial compounds for the skin are injected into the deeper layers of the skin.

These nutrients, thanks to the microscopic channels created by the needles, penetrate into the deeper layers of the skin and have positive effects on the structure and function of skin cells. The result of this process is a significant increase in the skin’s ability to absorb substances, stimulation of new collagen and elastin production, and improvement in the texture and tone of the skin. Over time, this method restores radiance, softness, and youthfulness to the skin and reduces issues such as fine lines, wrinkles, scars and acne marks, and skin dryness.
Side Effects of Mesoneedling
The side effects of mesoneedling involve a few considerations. In general, the treated areas heal quickly after the needling process. However, some occasional side effects may occur, including the following:
Skin Inflammation and Swelling
After undergoing mesoneedling, the skin may experience inflammation and swelling, which usually improves within a few days.

Skin Infection or Herpes Simplex Virus
In some rare cases, skin infections or the activation of the herpes simplex virus may occur, which requires treatment.
Milia
Milia, or small white bumps on the skin, may appear after mesoneedling, but this side effect is easily treatable.
Acne Flare-Up
Some individuals may experience an acne flare-up after mesoneedling, but this is usually mild and resolves quickly.
Contraindications for Mesoneedling
Mesoneedling is a safe and effective method for treating skin wrinkles and rejuvenating the skin. However, in some situations, this procedure is not recommended or should be performed with extra caution. These situations include:
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Presence of active skin infections such as herpes or chickenpox, which can spread and worsen with injection.
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History of keloid formation (scar tissue) due to skin injury, which increases the risk of scarring after the procedure.
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Use of blood-thinning or anticoagulant medications such as warfarin, which can lead to severe bleeding after the injection.
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Weakened immune system for any reason, including the use of immunosuppressive drugs, uncontrolled diabetes, or having autoimmune diseases, which increase the risk of infection and delayed wound healing.
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History of severe allergic reactions to any components of mesotherapy cocktails, which can lead to dangerous allergic responses.
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Presence of masses, wounds, or skin lesions at the injection site, which can increase the risk of infection or other complications.
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Pregnancy or breastfeeding, as the effects of mesotherapy on the fetus or breastfeeding infant are not fully understood.
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History of bleeding disorders or severe anemia, which can increase the risk of bleeding.
If any of these conditions are present, it is essential to consult with a specialist before undergoing mesotherapy so that they can assess potential risks and make the appropriate decision.
Post-Mesoneedling Care
Following proper post-mesoneedling care is extremely important, as these measures help prevent complications. After the procedure, skin redness is completely normal and usually resolves within a week or less. The duration of redness depends on your skin type. Here are some important points to follow after mesoneedling:
Avoid Makeup:
Refrain from using makeup for five days after the procedure.
Avoid Exercise:
Do not exercise for 24 hours after mesoneedling.
Avoid Injections and Tanning:
Do not get any dermal filler injections or tan your body for seven days.
Avoid Swimming and Heat:
During the first week after treatment, avoid swimming, saunas, hot showers, and tanning beds.
Do Not Touch or Rub the Treated Area:
Strictly avoid touching or rubbing the area where mesoneedling was performed.
Avoid Certain Products:
Do not use products that contain glycolic acid or retinol.
Post-mesoneedling care is very important, and if you follow all these tips for a short period, there is no need to worry. Since mesoneedling has a short recovery period, it has become one of the most popular methods.
Applications of Facial Mesoneedling
Mesoneedling is an effective method for reducing skin wrinkles and improving skin elasticity. Among the applications of facial mesoneedling, it can be mentioned that this method can also remove scars, pimples, and acne, and in some cases, it is used to reduce skin pigmentation. The type and amount of materials used in this method are determined according to each person’s specific needs and at the discretion of an experienced specialist. This technique improves blood circulation under the skin and reduces the size of pores, helping to prevent blackheads. Mesoneedling can be used on various areas of the body, including the face, hands, neck, and other sensitive areas.
Mesoneedling is especially suitable for reducing wrinkles around the eyes and other sensitive areas of the body. In addition, it is also used to treat hair problems; it can help prevent hair loss and, by strengthening the cells that produce hair follicles, contribute to stronger and healthier hair growth.
Mesoneedling for Facial Spots
Sometimes, mesoneedling is used to eliminate facial spots. The type of cocktail and injectable medications used in mesoneedling for facial spots is chosen based on individual conditions, skin type, and the severity of pigmentation. In this method, the production of new cells replaces damaged cells, and blood circulation in the treated area increases, which helps remove facial spots. The number of treatment sessions and the longevity of the results depend on the skin’s condition and the expertise of the specialist.
Mesoneedling for Acne Scars
Mesoneedling is an effective method for treating various types of acne, including blackheads, subcutaneous pimples, and inflammatory acne. In mesoneedling for acne scars, very thin and fine needles deliver therapeutic substances into the deeper layers of the skin, which accelerates the healing process and reduces inflammation and redness of the pimples. Additionally, by stimulating the production of collagen and elastin, this method can improve skin structure and help prevent new breakouts. To achieve better and more lasting results, several treatment sessions at specific intervals may be required, as determined by a specialist.

Hair Mesoneedling
Hair mesoneedling is a technique in which a microneedling device equipped with fine needles is used to create tiny injuries on the scalp. This process stimulates the skin’s natural response, increases blood circulation, and encourages the production of collagen and elastin. These effects can enhance the delivery and absorption of topical treatments and nutrients, resulting in healthier hair growth. The microchannels also help activate dormant hair follicles, potentially reversing hair loss and improving the overall density and thickness of the hair.
Cost of Facial Mesoneedling
The cost of facial mesoneedling is influenced by various factors, including the size of the treatment area, the depth of skin problems, the type of materials and medications used, the location of the clinic, the expertise and experience of the physician, and other variables. Costs may also vary between different clinics and doctors. Due to this diversity and complexity, it is not possible to set a fixed price for this treatment. It is best to contact your chosen clinic for more accurate information and a consultation about the costs. The experts will provide you with precise and appropriate details and help you choose the best treatment plan based on your needs.
Pre-Mesoneedling Measures
Before undergoing the procedure, it is essential to follow certain guidelines to prevent potential risks and side effects. Pre-mesoneedling measures include the following:
- Avoid taking blood-thinning medications such as aspirin, ibuprofen, and anticoagulant drugs at least 2 to 3 days before mesotherapy to prevent excessive bleeding.
- Do not use retinol and products containing retinoids a few days prior to treatment, as they may cause sensitivity and skin reactions.
- Inform your doctor about any medications or supplements you are taking, especially anti-inflammatory drugs and immunosuppressants.
- Avoid dermal filler injections, Botox, or any other cosmetic procedures at least 2 weeks before mesotherapy to prevent complications and interference with the treatment process.
- Thoroughly wash your face on the day of mesotherapy and avoid using makeup, creams, or any cosmetic or skincare products.
- Do not inject fillers, fat, or any other substances into the face for at least one month before mesotherapy to prevent infection and possible side effects.
- Avoid direct sun exposure, tanning beds, or sunbathing before treatment.
- Do not consume cigarettes or alcoholic beverages for a few days prior to mesotherapy, as they can negatively affect the healing and skin repair process.
- Inform your doctor if you have a history of cold sores or currently have an active cold sore, to prevent recurrence or spread.
- Inform your doctor about any underlying medical conditions such as diabetes, blood clotting disorders, or immune system diseases, due to the possibility of side effects.
Observing these important points before facial mesotherapy helps the doctor perform the treatment more cautiously and prevents potential complications. Also, following the doctor’s instructions can contribute to better and more successful treatment results.
Which Mesoneedling Clinic in Tehran Should I Visit?
Mesoneedling clinics in Tehran are among the leading beauty centers offering mesotherapy services. A mesoneedling clinic in Tehran, by utilizing experienced specialists, advanced equipment, and high-quality products, provides mesotherapy for treating facial wrinkles, skin spots, skin rejuvenation, and other skin imperfections. Reputable clinics in Tehran not only adhere to safety and hygiene standards but also place special emphasis on pre-treatment consultations to select the best method for each patient. In fact, these centers, by offering professional services and satisfactory results, are an excellent option for those looking for ways to rejuvenate and enhance the beauty of their skin.






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